Bruce C Trapnell Selected Research

Ileal Diseases

9/2013	Increased prevalence of luminal narrowing and stricturing identified by enterography in pediatric Crohn's disease patients with elevated granulocyte-macrophage colony stimulating factor autoantibodies.
2/2012	Innate dysfunction promotes linear growth failure in pediatric Crohn's disease and growth hormone resistance in murine ileitis.
12/2011	Granulocyte-macrophage colony stimulating factor blockade promotes ccr9(+) lymphocyte expansion in Nod2 deficient mice.
5/2011	Granulocyte macrophage-colony-stimulating factor autoantibodies and increased intestinal permeability in Crohn disease.

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Bruce C Trapnell Research Topics

Disease

34	Pulmonary Alveolar Proteinosis 01/2022 - 01/2002
17	Lung Diseases (Lung Disease) 01/2022 - 10/2008
10	Respiratory Insufficiency (Respiratory Failure) 01/2022 - 03/2009
7	Cystic Fibrosis (Mucoviscidosis) 01/2020 - 12/2009
7	Infections 01/2018 - 12/2002
6	Crohn Disease (Crohn's Disease) 01/2018 - 04/2009
5	Lymphangioleiomyomatosis (Lymphangiomyomatosis) 01/2019 - 09/2010
4	Autoimmune Diseases (Autoimmune Disease) 11/2014 - 03/2009
4	Ileal Diseases 09/2013 - 05/2011
3	Interstitial Lung Diseases (Interstitial Lung Disease) 01/2022 - 10/2004
3	Disease Progression 01/2022 - 01/2019
3	Pneumonia (Pneumonitis) 06/2021 - 01/2018
3	Inflammation (Inflammations) 01/2020 - 05/2011
3	Emphysema 01/2020 - 09/2010
3	Tuberous Sclerosis (Bourneville's Disease) 01/2019 - 09/2010
3	Sepsis (Septicemia) 01/2018 - 07/2002
3	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2018 - 04/2009
3	Ileitis 02/2012 - 04/2009
2	Chronic Obstructive Pulmonary Disease (COPD) 01/2022 - 04/2011
2	Rare Diseases (Rare Disease) 01/2022 - 10/2020
2	COVID-19 06/2021 - 08/2020
2	Hypoxia (Hypoxemia) 10/2020 - 04/2008
2	Dyspnea (Shortness of Breath) 01/2016 - 11/2014
2	Pediatric Crohn's disease 09/2013 - 02/2012
2	Granuloma 06/2012 - 06/2005
2	Pulmonary Fibrosis (Fibrosing Alveolitis) 06/2012 - 10/2011
2	Fibrosis (Cirrhosis) 06/2012 - 10/2011
2	Exocrine Pancreatic Insufficiency 09/2011 - 12/2009
2	Acquired Pulmonary Alveolar Proteinosis 11/2009 - 04/2008
1	Asthma (Bronchial Asthma) 01/2022
1	Giant Cell Arteritis (Horton Disease) 01/2022
1	Chest Pain (Chest Pains) 10/2020
1	Fever (Fevers) 08/2020
1	Polycythemia (Erythrocytosis) 01/2020
1	Macrophage Activation Syndrome 11/2019
1	Ulcerative Colitis 01/2018
1	Hemoptysis 10/2015
1	Respiratory Sounds (Crackle) 10/2015
1	Tachypnea 10/2015
1	Pathologic Constriction (Stenosis) 09/2013
1	Cardiovascular Diseases (Cardiovascular Disease) 08/2013
1	Lymphadenopathy 08/2013
1	Lung Injury 08/2013
1	Neoplasm Metastasis (Metastasis) 08/2013
1	Cysts 08/2013
1	Neoplasms (Cancer) 08/2013
1	Vascular Diseases (Vascular Disease) 08/2013

Drug/Important Bio-Agent (IBA)

39	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 01/2022 - 01/2002
20	Surface-Active Agents (Surfactants)IBA 01/2022 - 02/2004
20	AutoantibodiesIBA 01/2022 - 02/2004
12	Biomarkers (Surrogate Marker)IBA 01/2022 - 04/2008
6	Pulmonary Surfactants (Pulmonary Surfactant)IBA 01/2022 - 04/2008
6	Granulocyte-Macrophage Colony-Stimulating Factor Receptors (GM-CSF Receptor)IBA 01/2022 - 11/2010
5	Proteins (Proteins, Gene)FDA Link 01/2022 - 05/2007
4	Pulmonary Surfactant-Associated Protein D (Surfactant Protein D)IBA 01/2022 - 07/2010
4	IndiumIBA 01/2022 - 06/2012
4	lipoarabinomannan (LAM)IBA 01/2019 - 09/2010
3	mavrilimumabIBA 01/2022 - 08/2020
3	Acetaminophen (Paracetamol)FDA LinkGeneric 01/2022 - 03/2009
3	Sirolimus (Rapamycin)FDA Link 01/2019 - 04/2011
3	AntibodiesIBA 01/2018 - 04/2011
3	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 02/2012 - 04/2009
3	Pharmaceutical PreparationsIBA 02/2012 - 12/2009
2	Monoclonal AntibodiesIBA 06/2021 - 08/2020
2	Interleukin-18 (Interleukin 18)IBA 11/2019 - 12/2002
2	trans-sodium crocetinate (crocetin)IBA 01/2019 - 09/2010
2	Anti-Bacterial Agents (Antibiotics)IBA 01/2018 - 01/2012
2	CholesterolIBA 01/2017 - 06/2012
2	LipidsIBA 01/2017 - 07/2010
2	indium tin oxideIBA 01/2016 - 11/2014
2	Vascular Endothelial Growth Factor DIBA 08/2013 - 09/2010
2	Messenger RNA (mRNA)IBA 02/2012 - 07/2010
2	CytokinesIBA 12/2011 - 08/2010
1	Prednisone (Sone)FDA LinkGeneric 01/2022
1	STAT5 Transcription FactorIBA 01/2022
1	C-Reactive ProteinIBA 06/2021
1	molgramostimIBA 10/2020
1	SmokeIBA 01/2020
1	Matrix Metalloproteinases (MMPs)IBA 01/2020
1	Interleukin-1 (Interleukin 1)IBA 01/2020
1	Bronchodilator Agents (Bronchodilators)IBA 01/2019
1	Interleukin-10 (Interleukin 10)IBA 01/2018
1	InterferonsIBA 01/2018
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2018
1	Phenobarbital (Luminal)FDA Link 09/2013
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 08/2013
1	Cholesterol Esters (Cholesteryl Esters)IBA 06/2012
1	SolutionsIBA 03/2012
1	PowdersIBA 03/2012
1	Mannitol (Osmitrol)FDA LinkGeneric 03/2012

Therapy/Procedure

14	Therapeutics 10/2020 - 07/2002
3	Enzyme Replacement Therapy 01/2020 - 12/2009
2	Artificial Respiration (Mechanical Ventilation) 08/2020 - 10/2015
2	Drug Therapy (Chemotherapy) 01/2018 - 01/2017
2	Cell- and Tissue-Based Therapy (Cell Therapy) 10/2014 - 08/2013
1	Biological Therapy 11/2019
1	Punctures 01/2018
1	Ligation 01/2018
1	Bone Marrow Transplantation (Transplantation, Bone Marrow) 10/2014
1	Transplantation 10/2014